Científicos médicos, excepto epidemiólogos

Peer Review

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

davila724.7k

Análisis de Datos

Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Follows scientific method framework. For open-ended ideation use scientific-brainstorming; for automated LLM-driven hypothesis testing on datasets use hypogenic.

Depuración

Pathml

Full-featured computational pathology toolkit. Use for advanced WSI analysis including multiplexed immunofluorescence (CODEX, Vectra), nucleus segmentation, tissue graph construction, and ML model training on pathology data. Supports 160+ slide formats. For simple tile extraction from H&E slides, histolab may be simpler.

Scientific Critical Thinking

Evaluate scientific claims and evidence quality. Use for assessing experimental design validity, identifying biases and confounders, applying evidence grading frameworks (GRADE, Cochrane Risk of Bias), or teaching critical analysis. Best for understanding evidence quality, identifying flaws. For formal peer review writing use peer-review.

Diffdock

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

Computación Científica

Primekg

Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological data including genes, drugs, diseases, phenotypes, and more.

Bienestar y Salud

TCM Biomedical Research Strategist

Designs complete, rigorous research plans for medicinal plant / TCM molecular mechanism studies against diseases (colorectal cancer, liver cancer, diabetes, etc.). Use whenever a user provides a broad herbal medicine or network pharmacology research direction and wants it translated into a structured, executable, methodologically defensible study plan. Triggers: "research plan for herbal medicine", "network pharmacology study design", "TCM against cancer", "compound-target-pathway analysis", "hub gene identification", "immune microenvironment + natural products", "molecular docking study design", or any bioinformatics-driven pharmacology study from scratch. Always use this skill — do not improvise — when the user wants a full study framework.

Ventas y Marketing

Vaccine Design Orchestrator

Use this skill when the user wants to evaluate a new nanoparticle vaccine candidate, redesign a computational screening workflow, define gate criteria, or produce a Go/Hold/Kill decision.

Productividad e Integración

Drugflow Skills

Multi-flow API workflow skill for this DrugFlow Django repository. Use when an agent needs executable end-to-end API procedures such as login/register, workspace and balance retrieval, job listing, virtual screening, docking, ADMET, rescoring, structure extraction, and molecular factory.

Variant Pathogenicity Predictor

Integrate REVEL, CADD, PolyPhen scores to predict variant pathogenicity.

Análisis de Datos

Research Swarm TNBC Research Skill

Contribute scientific research findings to the Research Swarm TNBC (Triple-Negative Breast Cancer) mission. Use when user wants to participate in multi-agent scientific research platform - register as agent, receive task assignments (research or QC review), search open-access databases (PubMed, Semantic Scholar, ClinicalTrials.gov), submit cited findings. Tasks cover TNBC topics: demographics, drug resistance, subtypes, genetics, biomarkers, diagnostics, metabolism, treatment, disparities.

Ingeniería de Datos

Toxicity Structure Alert

Analyze data with `toxicity-structure-alert` using a reproducible workflow, explicit validation, and structured outputs for review-ready interpretation.

Bioinformática

Crispr Grna Designer

Design CRISPR gRNA sequences for specific gene exons with off-target prediction and efficiency scoring. Trigger when user needs gRNA design, CRISPR guide RNA selection, or genome editing target analysis.

Digital Twin Patient Builder

Build digital twin patient models to test drug efficacy and toxicity in virtual environments

Pubmed Search Specialist

Build complex Boolean query strings for precise PubMed/MEDLINE literature retrieval. Trigger when user needs MeSH term mapping, Boolean query construction, advanced PubMed filters, citation searching, systematic review search strategy, or clinical query optimization.

Análisis de Datos

Table 1 Generator

Automated generation of baseline characteristics tables (Table 1) for clinical research papers.

Herramientas de Laboratorio

Co2 Tank Monitor

IoT monitoring simulation to predict CO2 tank depletion and prevent weekend gas outages in cell culture facilities. Monitors cylinder pressure, calculates consumption rates, and provides early warnings for timely replacement.

Computación Científica

Version Compatibility

Estimate causal effects between exposures and outcomes using genetic variants as instrumental variables with TwoSampleMR. Implements IVW, MR-Egger, weighted median, and MR-PRESSO methods for robust causal inference from GWAS summary statistics. Use when testing whether an exposure causally affects an outcome using genetic instruments.

FreedomIntelligence2.1k

Literature Review

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).

Fda Database

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

DrugBank Database

Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task requiring detailed drug and drug target information from DrugBank.

Productividad e Integración

Pubmed Database

Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.

Zinc Database

Access ZINC (230M+ purchasable compounds). Search by ZINC ID/SMILES, similarity searches, 3D-ready structures for docking, analog discovery, for virtual screening and drug discovery.

Chembl Database

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Peer Review

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

K-Dense-AI1.6k

Tooluniverse Clinical Guidelines

Search and retrieve clinical practice guidelines across 12+ authoritative sources including NICE, WHO, ADA, AHA/ACC, NCCN, SIGN, CPIC, CMA, CTFPHC, GIN, MAGICapp, PubMed, EuropePMC, TRIP, and OpenAlex. Use when users ask about clinical guidelines, treatment recommendations, standard of care, evidence-based medicine, or drug-gene dosing recommendations.

Bioinformática

COMPUTE, DON'T DESCRIBE

Rare disease genomics research -- disease identification via Orphanet, causative gene discovery, gene-disease validity assessment via GenCC, pathogenic variant lookup via ClinVar, HPO phenotype mapping, epidemiology and prevalence data, clinical trial search, and literature review. Use when users ask about rare diseases, orphan diseases, genetic causes of rare conditions, Orphanet codes, HPO phenotypes, gene-disease validity, rare disease prevalence, or treatment options for rare genetic disorders.

Tooluniverse Drug Mechanism Research

Drug mechanism of action investigation -- systematic strategy to trace a drug from its primary target through pathways to clinical outcomes, identify off-target effects, and combine regulatory labels with literature evidence for a complete mechanism picture.

Vaccine Design

Design and evaluate vaccine candidates using computational immunology tools. Covers epitope prediction (MHC-I/II binding via IEDB), population coverage analysis, antigen selection, adjuvant matching, and immunogenicity assessment. Integrates IEDB for epitope prediction, UniProt for antigen sequences, PDB/AlphaFold for structural epitopes, BVBRC for pathogen proteomes, and literature for clinical precedent. Use when asked about vaccine design, epitope prediction, immunogenicity, MHC binding, T-cell epitopes, B-cell epitopes, or population coverage for vaccine candidates.

Finanzas e Inversión

Clinical Trial Design Feasibility Assessment

Strategic clinical trial design feasibility assessment using ToolUniverse. Evaluates patient population sizing, biomarker prevalence, endpoint selection, comparator analysis, safety monitoring, and regulatory pathways. Creates comprehensive feasibility reports with evidence grading, enrollment projections, and trial design recommendations. Use when planning Phase 1/2 trials, assessing trial feasibility, or designing biomarker-driven studies.