Query and annotate gene variants from ClinVar and dbSNP databases. Trigger when: - User provides a variant identifier (rsID, HGVS notation, genomic coordinates) and asks about clinical significance - User mentions "ClinVar", "dbSNP", "variant annotation", "pathogenicity", "clinical significance" - User wants to know if a mutation is pathogenic, benign, or of uncertain significance - User provides VCF content or variant data requiring interpretation - Input: variant ID (rs12345), HGVS notation (NM_007294.3:c.5096G>A), or genomic coordinates (chr17:43094692:G>A) - Output: clinical significance, ACMG classification, allele frequency, disease associations

openclaw4.2k

Herramientas de Laboratorio

Heatmap Beautifier

Professional beautification tool for gene expression heatmaps, automatically adds clustering trees, color annotation tracks, and intelligently optimizes label layout.

openclaw4.2k

Química Computacional

Buffer Calculator

Calculate complex buffer recipes with precise measurements for molecular biology and biochemistry applications. Provides accurate mass/volume calculations, pH considerations, and step-by-step preparation instructions.

openclaw4.2k

Química Computacional

Blockbuster Therapy Predictor

Predict which early-stage biotechnology platforms (PROTAC, mRNA, gene editing, etc.) have the highest potential to become blockbuster therapies. Analyzes clinical trial progression, patent landscape maturity, and venture capital funding trends to generate investment and R&D prioritization scores. Trigger when: User asks about technology investment potential, platform selection, or therapeutic modality comparison.

openclaw4.2k

Bioinformática

Auto Proteomics

Public OpenClaw skill for low-token routing and downstream analysis of processed DDA LFQ proteomics inputs. Use when the user already has protein-level quantification tables such as MaxQuant-style `proteinGroups.txt` and needs a clear two-group downstream workflow.

openclaw4.2k

Química Computacional

Crispr Screen Analyzer

Process CRISPR screening data to identify essential genes and hit candidates. Performs quality control, statistical analysis (RRA), and hit calling for pooled CRISPR screens including viability screens and drug resistance/sensitivity studies.

openclaw4.2k

Gestión de Proyectos

Resubmission Deadline Tracker

Track manuscript resubmission deadlines and automatically generate phase-appropriate task breakdowns for academic researchers based on remaining time.

openclaw4.2k

Bioinformática

Scrna Cell Type Annotator

Auto-annotate cell clusters from single-cell RNA data using marker genes.

openclaw4.2k

Bioinformática

Cnv Caller Plotter

Detect copy number variations from whole genome sequencing data and generate publication-quality genome-wide CNV plots. Supports CNV calling, segmentation, and visualization for cancer genomics and rare disease analysis.

openclaw4.2k

Académico

Paper Term Translation

Translate generalized descriptions in questions into precise academic terminology for effective paper search

EverMind-AI4.1k

Académico

Paper Numeric Anchor

Use specific numerical values (sample sizes, percentages, citation counts) as strong search anchors to locate research papers

EverMind-AI4.1k

Seguridad

Papersgpt For Zotero

A privacy-first, local-first search assistant and MCP server for your Zotero library, enabling AI agents to search and analyze your research papers securely.

papersgpt2.3k

CI/CD

Experiment

Use when a quest is ready for a concrete implementation pass or a main experiment run tied to a selected idea and an accepted baseline.

ResearAI2.3k

Depuración

Analysis Campaign

Use when a quest needs one or more follow-up runs such as ablations, robustness checks, error analysis, or failure analysis after a main experiment.

ResearAI2.3k

Depuración

Finalize

Use when the quest is ready to consolidate final claims, limitations, recommendations, summary state, and graph exports before stopping or archiving.

ResearAI2.3k

Depuración

Figure Polish

Use when a quest needs a polished milestone chart, paper-facing figure, appendix figure, or a mandatory render-inspect-revise pass before treating a figure as final.

ResearAI2.3k

LLM & AI

Idea

Use when a quest needs concrete hypotheses, limitation analysis, candidate directions, or a selected idea relative to the active baseline.

ResearAI2.3k

Ventas y Marketing

Intake Audit

Use when a quest does not start from a blank state and the agent must first audit, trust-rank, and reconcile existing baselines, results, drafts, or review materials before choosing the next anchor.

ResearAI2.3k

Base de Conocimientos

Baseline

Use when a quest needs to attach, import, reproduce, repair, verify, compare, or publish a baseline and its metrics.

ResearAI2.3k

Bioinformática

Biological Sequence Retrieval

Retrieves biological sequences (DNA, RNA, protein) from NCBI and ENA with gene disambiguation, accession type handling, and comprehensive sequence profiles. Creates detailed reports with sequence metadata, cross-database references, and download options. Use when users need nucleotide sequences, protein sequences, genome data, or mention GenBank, RefSeq, EMBL accessions.

FreedomIntelligence2.1k

Bioinformática

Bio De Edger Basics

Perform differential expression analysis using edgeR in R/Bioconductor. Use for analyzing RNA-seq count data with the quasi-likelihood F-test framework, creating DGEList objects, normalization, dispersion estimation, and statistical testing. Use when performing DE analysis with edgeR.

FreedomIntelligence2.1k

Bioinformática

Bio Pathway Reactome

Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database. Performs over-representation analysis and GSEA with visualization and pathway hierarchy exploration.

FreedomIntelligence2.1k

Bioinformática

Bio Variant Normalization

Normalize indel representation and split multiallelic variants using bcftools norm. Use when comparing variants from different callers or preparing VCF for downstream analysis.

FreedomIntelligence2.1k

Herramientas de Laboratorio

Bio Alignment Msa Statistics

Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics. Use when comparing alignment quality, measuring sequence divergence, and analyzing evolutionary patterns.

FreedomIntelligence2.1k

Bioinformática

Bio Variant Calling

Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments.

FreedomIntelligence2.1k

Bioinformática

Bio Pathway Kegg Pathways

KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a gene list. Supports 4000+ organisms via KEGG online database.

FreedomIntelligence2.1k

Bioinformática

Bio De Results

Extract, filter, annotate, and export differential expression results from DESeq2 or edgeR. Use for identifying significant genes, applying multiple testing corrections, adding gene annotations, and preparing results for downstream analysis. Use when filtering and exporting DE analysis results.

FreedomIntelligence2.1k

Análisis de Datos

Bio Vcf Statistics

Generate variant statistics, sample concordance, and quality metrics using bcftools stats and gtcheck. Use when evaluating variant quality, comparing samples, or summarizing VCF contents.

FreedomIntelligence2.1k

Bioinformática

Gene Expression & Omics Data Retrieval

Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports. Creates comprehensive dataset profiles with metadata, sample information, and download links. Use when users need expression data, omics datasets, or mention ArrayExpress (E-MTAB, E-GEOD) or BioStudies (S-BSST) accessions.

FreedomIntelligence2.1k

Académico

Scientific Critical Evaluation and Peer Review

Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.

foryourhealth111-pixel1.6k

Otros científicos biológicos | Skills Pool