Applies USPSTF screening recommendations by age, sex, and risk factors. Use when ordering preventive screenings, creating screening schedules, or applying evidence-based prevention guidelines.
Applies USPSTF screening recommendations by age, sex, and risk factors.
The U.S. Preventive Services Task Force (USPSTF) issues evidence-based screening recommendations graded A through D, plus "I" (insufficient evidence). Grade A and B recommendations carry a mandate under the ACA: non-grandfathered health plans must cover these services with zero cost-sharing. Failure to apply USPSTF guidelines results in missed cancers, undetected cardiovascular risk, and preventable morbidity—while also exposing practices to quality measure penalties under MIPS (Merit-based Incentive Payment System).
Primary care clinicians must match the right screening to the right patient at the right interval. Over-screening (e.g., PSA without shared decision-making, mammography in low-risk women under 40) drives unnecessary biopsies and patient anxiety. Under-screening (e.g., missed lung cancer screening in eligible smokers, skipped HCV testing) misses the window for curative intervention. This skill maps USPSTF grades to patient demographics to produce a precise, defensible screening schedule.
These USPSTF Grade A/B recommendations apply regardless of specific risk factors:
| Screening | Population | Interval | Grade |
|---|---|---|---|
| Blood pressure | Adults ≥18 | Annually if normal; confirm elevated with ABPM/HBPM | A |
| Depression (PHQ-2/PHQ-9) | Adults ≥18 | Annually with adequate systems for treatment | B |
| HIV | Adults 15-65 | At least once; more frequently if high-risk | A |
| Hepatitis C (anti-HCV) | Adults 18-79 | Once (unless ongoing risk) | B |
| Hepatitis B (HBsAg) | Adolescents and adults at increased risk | Per risk assessment | B |
| Unhealthy alcohol use (AUDIT-C) | Adults ≥18 | Annually with brief intervention | B |
| Unhealthy drug use | Adults ≥18 | Annual screening with brief intervention | B |
| Obesity (BMI) | Adults ≥18 | Every visit; refer to intensive behavioral counseling if BMI ≥30 | B |
| Tobacco use | Adults ≥18 | Every visit; offer cessation interventions | A |
| Statin for CVD prevention | Adults 40-75 with ≥1 CVD risk factor and 10-year risk ≥10% | Per ASCVD risk calculation | B |
| Prediabetes/T2DM | Adults 35-70 who are overweight or obese | Every 3 years if normal | B |
| Cancer | Population | Method | Interval | Grade | Notes |
|---|---|---|---|---|---|
| Breast | Women 50-74 | Mammography | Every 2 years | B | 40-49: individualized per 2024 update (Grade B) |
| Cervical | Women 21-65 | Pap alone (21-29); Pap+HPV co-test or HPV primary (30-65) | Every 3 years (Pap); every 5 years (co-test/HPV primary) | A | Stop at 65 if adequate prior screening |
| Colorectal | Adults 45-75 | Colonoscopy q10y, FIT annually, FIT-DNA q1-3y, CT colonography q5y | Per modality | A | 76-85: individualized (Grade C) |
| Lung | Adults 50-80, ≥20 pack-year history, current or quit <15 years | Low-dose CT (LDCT) | Annually | B | Shared decision-making required |
| Prostate | Men 55-69 | PSA | Individualized | C | Shared decision-making required; Grade D for ≥70 |
| Skin | General population | Whole-body exam | N/A | I | Insufficient evidence for routine screening |
| Screening | Population | Interval | Grade |
|---|---|---|---|
| Chlamydia | Sexually active women ≤24; older women at increased risk | Annually | B |
| Gonorrhea | Sexually active women ≤24; older women at increased risk | Annually | B |
| Syphilis | Persons at increased risk | Per risk assessment | A |
| Intimate partner violence | Women of reproductive age | Screening with referral resources | B |
| Preeclampsia prevention | Pregnant women at high risk | Low-dose aspirin after 12 weeks gestation | B |
| Gestational diabetes | Pregnant women ≥24 weeks | OGTT or two-step glucose challenge | B |
| Rh incompatibility | Pregnant women at first prenatal visit | Blood typing and antibody screen | A |
| BRCA-related cancer risk | Women with family history suggestive of BRCA1/2 | Risk assessment tool → genetic counseling referral | B |
Generate a schedule customized to the patient's age band:
Ages 18-39:
Ages 40-49:
Ages 50-64:
Ages 65-75:
Ages 76+:
For each screening: