Active targeting skill for designing and validating nanoparticle targeting strategies
The Targeting Ligand Designer skill provides systematic design of active targeting strategies for nanoparticle drug delivery, enabling selection and validation of targeting moieties for specific cellular or tissue targets.
Ligand Selection
Conjugation Optimization
Validation
{
"target_receptor": "string",
"cell_type": "string",
"nanoparticle_type": "string",
"ligand_candidates": ["string"],
"required_specificity": "number (fold)"
}
{
"recommended_ligand": {
"name": "string",
"type": "antibody|peptide|aptamer|small_molecule",
"Kd": "number (nM)"
},
"conjugation_strategy": {
"chemistry": "string",
"ligand_density": "number (ligands/NP)",
"orientation": "string"
},
"predicted_performance": {
"specificity": "number (fold)",
"uptake_enhancement": "number (fold)"
}
}