Use when adding Stockholm sequence-weight annotations to nucleotide or protein MSAs before downstream HMMER-style modeling.
esl-weight [options] <msafile>/home/vimalinx/miniforge3/envs/bio/bin/esl-weightreferences/help.md for the current startup failure; option details below are grounded in the local man page plus binary strings.esl-weight when you need per-sequence weights written back into a multiple alignment as Stockholm #=GS <seqname> WT <weight> annotation.-g for Gerstein/Sonnhammer/Chothia weights, -p for Henikoff position-based weights, or -b for BLOSUM-style cluster weights.# Default Gerstein/Sonnhammer/Chothia weighting
esl-weight alignment.sto > weighted.sto
# Faster Henikoff position-based weighting
esl-weight -p alignment.sto > pb-weighted.sto
# BLOSUM-style clustering weights at a chosen identity threshold
esl-weight -b --id 0.70 alignment.sto > blosum70.sto
# Force protein alphabet when autodetection is ambiguous
esl-weight --amino alignment.sto > weighted-aa.sto
--amino, --dna, or --rna if autodetection could be ambiguous.#=GS ... WT lines are present.libopenblas.so.0 is missing. Until that library issue is fixed, -h and live runtime validation are unavailable.-g as the default, -p as Henikoff position-based weighting, and -b as BLOSUM-style clustering weights.--id <x> only applies with -b; the documented default threshold is 0.62.WT annotations even if the input alignment came from another accepted format.