Esummary

# 2) SRA summary in JSON
esummary -db sra -id SRR5437876 -mode json

# 3) Search then summarize
esearch -db biosample -query 'SAMN03737421' | esummary

Recommended Workflow

1. Use esearch or known accessions to get the relevant record IDs.
2. Fetch summaries first to inspect metadata before pulling full records.
3. Switch to -mode json only if your downstream tooling benefits from it.
4. Use xtract on XML summaries when you need a quick tabular extract.

Guardrails

• esummary returns summaries, not full records or raw sequence payloads.
• Database names and accession styles are database-specific; validate them with einfo or esearch if unsure.
• Use -raw only when you know the database-specific XML rewriting is getting in your way.
• Network connectivity to NCBI is required for all operations.