Query 14+ biomedical databases for drug repurposing, target discovery, clinical trials, and literature research. Access ChEMBL, PubMed, ClinicalTrials.gov, OpenTargets, OpenFDA, OMIM, Reactome, KEGG, UniProt, and more through a unified MCP endpoint. Use when researching disease targets, finding approved/investigational drugs, searching clinical evidence, discovering genetic associations, or analyzing compound bioactivity data.
Query 14+ biomedical databases for drug repurposing, target discovery, clinical evidence, and literature research — all via a unified MCP endpoint.
# Find drugs for myasthenia gravis
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"chembl_find_drugs_by_indication","arguments":{"indication":"myasthenia gravis","max_results":10}},"id":1}'
That's it! You now have approved and investigational drugs for the disease.
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"chembl_find_drugs_by_indication","arguments":{"indication":"myasthenia gravis","max_results":20}},"id":1}'
Returns: Approved + investigational drugs with max phase reached
# First: Find disease ID
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"opentargets_search","arguments":{"query":"myasthenia gravis","entity_type":"disease"}},"id":1}'
# Returns: disease ID (e.g., EFO_0004991)
# Then: Get targets
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"opentargets_get_associations","arguments":{"disease_id":"EFO_0004991","size":20}},"id":2}'
Returns: Top disease targets ranked by evidence strength (0-1 score)
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"pubmed_search_articles","arguments":{"diseases":["myasthenia gravis"],"keywords":["immunotherapy"],"max_results":20}},"id":1}'
Returns: PubMed articles on myasthenia gravis immunotherapy
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"ctg_search_studies","arguments":{"condition":"myasthenia gravis","recruitment_status":"RECRUITING","max_results":20}},"id":1}'
Returns: Actively recruiting trials for the disease
curl -X POST https://mcp.cloud.curiloo.com/tools/unified/mcp \
-H "Content-Type: application/json" -H "Accept: application/json" \
-d '{"jsonrpc":"2.0","method":"tools/call","params":{"name":"openfda_search_adverse_events","arguments":{"drug_name":"eculizumab","limit":50}},"id":1}'
Returns: FDA adverse event reports—check for serious outcomes, death, hospitalization
14+ Integrated Databases
| Database | What's Inside | Use For |
|---|---|---|
| ChEMBL | 2M drugs, bioactivity data | Finding approved/investigational drugs |
| OpenTargets | Disease-target links + evidence | Identifying therapeutic targets |
| PubMed | 35M+ articles + preprints | Literature review & validation |
| ClinicalTrials.gov | 400K+ active trials | Finding ongoing studies |
| OpenFDA | Adverse events, drug labels | Safety assessment |
| OMIM | Genetic diseases, genes → phenotypes | Understanding disease genetics |
| Reactome | Pathways, protein interactions | Mechanism understanding |
| UniProt | Protein sequences, annotations | Protein properties |
| KEGG | Metabolic & disease pathways | Systems-level view |
| GWAS Catalog | Genetic associations | Variant discovery |
| Pathway Commons | Integrated pathway data | Network analysis |
| MyGene.info | Gene annotations | ID mapping |
| MyVariant.info | Variant effects | Variant interpretation |
| + more |
Find non-standard-care drugs for rare/complex diseases:
Identify novel therapeutic targets:
Compile evidence for a hypothesis:
Systematically search biomedical research:
Production (No setup needed):